Genotoxicity of GAL-57 Herbicide in Salmonella typhimurium and Escherichia coli
Ispitivanja genotoksičnosti herbicida GAL-57 na Salmonella typhimurium i Escherichia coli
dc.contributor.author | Brkic, Dragica | |
dc.contributor.author | Gasic, Slavica | |
dc.contributor.author | Vertesi, Adel | |
dc.contributor.author | Karan, Vesela | |
dc.contributor.author | Neskovic, Nesko | |
dc.date.accessioned | 2015-10-31T16:46:42Z | |
dc.date.available | 2015-10-31T16:46:42Z | |
dc.identifier.uri | http://arhiva.nara.ac.rs/handle/123456789/1261 | |
dc.description.abstract | Genotoxicity of the herbicide GAL-57, containing two active ingredients; bentazon and dicamba, was investigated using the Ames test. Salmonella typhimurium (tester strains TA98 and TA100) and Escherichia coli (strain WP2uvrA) were used. Nine product concentrations were tested at a range of 19.53-5000 μg/plate and each concentration, as well as the controls, in triplicate. Testing was done with and without metabolic activation (liver microsomal fraction, S-9 mix). The results of our investigation revealed no biological or statistically significant increase in mutagenic factors, and this offered a basis for our conclusion that the herbicide GAL-57 has no genotoxic properties (with or without metabolic activation) under experimental conditions in the Ames test. | en |
dc.description.abstract | Genotoksična svojstva herbicida GAL-57, koji u svom sastavu ima dve aktivne materije, bentazon i dikambu, ispitivana su primenom Ames-ovog testa. Korišćene su bakterije Salmonella typhimurium (sojevi TA98 i TA100) i Escherichia coli (WP2uvrA soj). Ispitivano je devet koncentracija preparata u opsegu 19.53-5000 μg/ploča pri čemu je svaka koncentracija, kao i kontrole, testirana po tri puta. Ispitivanje je obavljeno sa i bez metaboličke aktivacije (mikrozomska frakcija jetre, S-9 mix). Rezultati ispitivanja su pokazali da nema ni biološki ni statistički značajnog povećanja faktora mutacije na osnovu čega se zaključuje da herbicid GAL-57, u eksperimentalnim uslovima Ames-ovog testa, ne poseduje genotoksična svojstva (sa i bez metaboličke aktivacije). | sr |
dc.subject | GAL-57 | sr |
dc.subject | Mutagenicity | en |
dc.subject | Bentazon | sr |
dc.subject | Dicamba | sr |
dc.subject | Ames test | sr |
dc.subject | mutagenost | sr |
dc.subject | bentazon | sr |
dc.subject | dikamba | sr |
dc.title | Genotoxicity of GAL-57 Herbicide in Salmonella typhimurium and Escherichia coli | en |
dc.title.alternative | Ispitivanja genotoksičnosti herbicida GAL-57 na Salmonella typhimurium i Escherichia coli | sr |
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VOL 21 *No.4
http://www.pesting.org.rs/2006.php